Table 6.
Results of voxelwise correlation analyses between longitudinal changes in FA and RD maps and concomitant changes in behavioral tests (p < 0.005 uncorrected).
| MNI coordinates |
||||||
|---|---|---|---|---|---|---|
| Cluster size | T | p | x | y | z | WM structures |
| FA - Originality ↑ | ||||||
| 34 | 2.65 | <0.001 | 15 | –2 | 7 | Right anterior thalamic radiation/ Right Posterior limb of internal capsule |
| 23 | 3.31 | <0.001 | –34 | –18 | 35 | Left superior longitudinal fasciculus |
| RD – Originality ↓ | ||||||
| 56 | 3.44 | <0.001 | –17 | –14 | 55 | Left superior longitudinal fasciculus |
| 38 | 4.26 | <0.001 | 16 | –2 | 6 | Right posterior limb of internal capsule |
| 31 | 3.31 | 0.001 | –29 | –3 | 27 | Left superior longitudinal fasciculus (temporal part) |
| FA – GSE ↑ | ||||||
| 82 | 3.33 | <0.001 | –23 | 18 | 13 | Left anterior thalamic radiation |
| 30 | 4.31 | <0.001 | –22 | –3 | 15 | Left anterior thalamic radiation / Left Anterior limb of internal capsule |
| 29 | 3.88 | 0.001 | 9 | –7 | 11 | Right anterior thalamic radiation |
| 24 | 4.79 | <0.001 | –37 | –24 | 31 | Left superior longitudinal fasciculus, Left Superior longitudinal fasciculus (temporal part) |
| RD – GSE ↓ | ||||||
| 29 | 3.51 | 0.001 | –21 | –3 | 16 | Left anterior thalamic radiation/Left anterior limb of internal capsule |
| 22 | 3.93 | <0.001 | –22 | 15 | 12 | Left anterior thalamic radiation/Left anterior limb of internal capsule |
Positive correlations were found between regions showing longitudinal increments of FA and both AUs originality and GSE scores at T1 respect to T0. Negative correlations were also found between longitudinal decrements of RD and improvements of originality and GSE scores at T1 respect to T0. Refer to Table 2 for a detailed explanation of the table layout.