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. 2017 Dec 11;7:17303. doi: 10.1038/s41598-017-17817-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Examples of Donggyeong dog-specific non-synonymous SNPs and consequential amino acid variants. Top panel shows gene structure with the direction of transcription (blue arrow). Bottom panel indicates positions of non-synonymous SNPs and comparison of amino acids among different dog breeds and related species. Two different amino acids corresponding to two nucleotide variants in Donggyeong dog are shown together with a slash delimiter. The dash symbol represents a gap in multiple sequene alignment. DG: Donggyeong dog, DQ: Diquing village dog, KM: Kunming dog, YJ: Yingjiang village dog, GS: German shepherd, LJ: Lijiang village dog, TM: Tibetan mastiff. Other dog breeds not shown here contained the same variant as dog breeds with blue color shown in this figure.