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. 2017 Dec 11;7:17303. doi: 10.1038/s41598-017-17817-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Evolutionary changes in protein interactions among Donggyeong dog tail-specific proteins against a total of 2,218 protein pairs (A) and non-tail-specific proteins against a total of 2,539 protein pairs (B). Numbers on branches represent the number of newly appeared (in the case of +) or disappeared (in the case of −) protein interactions. Percentages in parentheses indicate fraction against the number of protein pairs without interaction (in the case of +) or the number of protein pairs with interaction (in the case of −). Two numbers next to names of ancestors or above names of descendant species mean the number of protein pairs with or without interaction, respectively. Divergence time among species was obtained from the TimeTree website (http://www.timetree.org/).