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. 2017 Nov;15(8):1085–1092. doi: 10.2174/1567201814666161205131745

Table 6.

Observed and predicted Experimental Potential %values for tetra- variable model using SVM and MLR dataset 3 
(32 Compounds).

Experimental
Potential %
Predicted
Potential %
Predicted
Potential %
Linear (MLR) Non-linear (SVM)
Series I. Magnolol Analogues
R1 R2 R3
1 H pentyl H 5 4.4 0.9
2 H hexyl H 7 6.1 5.1
3 methyl butyl H 5 4.8 3.5
4 methyl pentyl H 3 3.5 2.6
5 methyl hexyl H 7 6.4 7.0
6 ethyl propyl H 5 4.4 5.0
7 ethyl butyl H 3 4.6 3.0
8 ethyl pentyl H 3 3.1 3.0
9 propyl pentyl H 5 5.3 3.9
10 propyl hexyl H 5 2.7 4.8
11 propyl heptyl H 1 1.1 3.2
12 propyl octyl H 1 -0.3 1.0
13 butyl pentyl H 5 6.2 3.9
14 butyl hexyl H 3 2.5 3.0
15 ethyl pentyl CH3 7 7.5 6.6
16 ethyl hexyl CH3 5 5.0 5.0
17 propyl pentyl CH3 1 3.3 3.0
18 propyl hexyl CH3 1 0.5 1.0
19 pentyl ethyl CH3 3 2.6 3.6
20 pentyl propyl CH3 3 3.5 3.0
21 hexyl propyl CH3 1 -0.1 0.8
Series II. 4’-O-methyl Honokiol Analogues
1 methyl methyl - 1 1.1 1.0
2 ethyl methyl - 3 2.8 3.0
3 propyl methyl - 10 9.2 10.0
4 butyl methyl - 10 8.9 10.0
5 pentyl methyl - 7 8.2 7.0
6 hexyl methyl - 10 8.5 9.6
7 heptyl methyl - 7 6.4 7.1
8 octyl methyl - 1 3.1 3.2
9 hexyl ethyl - 3 4.5 3.3
10 hexyl propyl - 1 2.6 1.0
11 hexyl isopropyl - 1 0.5 1.0