Table 2.

Characteristics of studies included in the systematic review of gastric cancer incidence in patients with intestinal metaplasia

First Author (year) [reference]	Country	Study Design	Indication for Endoscopy	Study follow up period	Outcome Source	Number of patients in cohort	Male (%)	Mean age (years)	Follow-up (years) [mean/median]	HP* positive (%)
Bleibel (2003) [39]	United States of America	Retrospective cohort	NR*	1993–2012	Cancer registry	675	49	61	5.3 (mean)	18
De Vries (2010) [40]	The Netherlands	Prospective cohort	NR*	2006–2007	Endoscopy	101	50	61	2.3 (mean)	18
González (2016) [38]	Spain	Retrospective cohort	NR*	1995–2013	Pathology records, clinical records, endoscopy	467	56	53	12 (mean)	56
Horsley-Silva (2015) [26]	United States of America	Retrospective cohort	Dyspepsia	2003–2004	NR*	200	50	68	4.1 (mean)	19
Kim (2008) [27]	Korea	Prospective cohort	NR*	1992–1998	Endoscopy	515	88	45	10.2 (mean)	78
Li (2016) [18]	United States of America	Retrospective cohort	NR*	1997–2013	Cancer registry, clinical records	4146	48	66	7.1 (median)	51
Reddy (2014) [19]	United States of America	Retrospective cohort	NR*	2000–2011	Cancer registry	907	NR*	68	4.6 (median)	NR*
Song (2015) [36]	Sweden	Retrospective cohort	NR*	1979–2011	Endoscopy, Cancer registry, ONS*	11,530	55	66	7.9 (mean)	NR*
Tava (2006) [12]	Italy	Retrospective cohort	Dyspepsia	1989–1997	Endoscopy	259	51	60	3.9 (median)	27

*NR Information not available, HP Helicobacter pylori, ONS Office for National Statistics