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. 2017 Sep 26;106(1):168–179. doi: 10.1002/jbm.a.36223

Figure 3.

Figure 3

Calcium chelation mechanism of the PVPA‐co‐AA polymer (A) PVPA‐co‐AA copolymer dissolves in aqueous solution to form a negatively‐charged polyelectrolyte. (B) PVPA‐co‐AA can bind to divalent calcium ions. (C) At high calcium concentrations, inter‐polymer complexes can be formed, resulting in a cloudy solution. (D) Precipitation of polymer‐calcium complex at very high calcium concentrations.