Skip to main content
. 2017 Nov 8;41(12):2066–2081. doi: 10.1111/acer.13511

Table 2.

Effects of Acute Ethanol (EtOH) and Acute Stress on CD11b Expression Across Brain Regions (% control)

Brain region CON E S E+S
Prefrontal cortex
PrL 100 ± 19a 100 ± 23a,b 94 ± 10a 167 ± 23b
IL 100 ± 21a 91 ± 18a,b 74 ± 6a 149 ± 23b
Nucleus accumbens
Core 100 ± 8a 109 ± 30a 127 ± 22a 195 ± 19b
Shell 100 ± 8a 97 ± 20a 126 ± 21a,b 169 ± 13b
Bed nucleus of the stria terminalis
dBNST 100 ± 14a 171 ± 56a,b 202 ± 25a,b 283 ± 30b
vBNST 100 ± 10a 138 ± 29a,b 215 ± 27a,b 247 ± 32b
Hypothalamus
PVN 100 ± 28a 126 ± 36a 551 ± 70b 361 ± 20b
Amygdala
BLA 100 ± 16a 112 ± 15a 129 ± 13a 207 ± 18b
CeA 100 ± 8a 108 ± 10a 99 ± 9a 153 ± 13b

BLA, basolateral amygdala; CeA, central nucleus of the amygdala; dBNST, dorsal bed nucleus of the stria terminalis; IL, infralimbic cortex; PVN, paraventricular nucleus of the hypothalamus; PrL, prelimbic cortex; vBNST, ventral bed nucleus of the stria terminalis.

Rats were treated simultaneously with acute EtOH and a 2‐hour restraint/water immersion stressor. The rats were then sacrificed immediately following the conclusion of the stressor. Brain regions were stained for CD11b to assess microglial activation. n = 4 to 10 per group. Data are presented as mean ± SEM. Statistically significant differences are indicated by different letters; for example, means with superscripts “a” and “b” are statistically different (Tukey's post hoc test), while means with superscripts “a” and “a” are not statistically different.