Table 2.
Brain region | CON | E | S | E+S |
---|---|---|---|---|
Prefrontal cortex | ||||
PrL | 100 ± 19a | 100 ± 23a,b | 94 ± 10a | 167 ± 23b |
IL | 100 ± 21a | 91 ± 18a,b | 74 ± 6a | 149 ± 23b |
Nucleus accumbens | ||||
Core | 100 ± 8a | 109 ± 30a | 127 ± 22a | 195 ± 19b |
Shell | 100 ± 8a | 97 ± 20a | 126 ± 21a,b | 169 ± 13b |
Bed nucleus of the stria terminalis | ||||
dBNST | 100 ± 14a | 171 ± 56a,b | 202 ± 25a,b | 283 ± 30b |
vBNST | 100 ± 10a | 138 ± 29a,b | 215 ± 27a,b | 247 ± 32b |
Hypothalamus | ||||
PVN | 100 ± 28a | 126 ± 36a | 551 ± 70b | 361 ± 20b |
Amygdala | ||||
BLA | 100 ± 16a | 112 ± 15a | 129 ± 13a | 207 ± 18b |
CeA | 100 ± 8a | 108 ± 10a | 99 ± 9a | 153 ± 13b |
BLA, basolateral amygdala; CeA, central nucleus of the amygdala; dBNST, dorsal bed nucleus of the stria terminalis; IL, infralimbic cortex; PVN, paraventricular nucleus of the hypothalamus; PrL, prelimbic cortex; vBNST, ventral bed nucleus of the stria terminalis.
Rats were treated simultaneously with acute EtOH and a 2‐hour restraint/water immersion stressor. The rats were then sacrificed immediately following the conclusion of the stressor. Brain regions were stained for CD11b to assess microglial activation. n = 4 to 10 per group. Data are presented as mean ± SEM. Statistically significant differences are indicated by different letters; for example, means with superscripts “a” and “b” are statistically different (Tukey's post hoc test), while means with superscripts “a” and “a” are not statistically different.