Figure 4.

Comparison of serum neuron‐specific enolase (NSE) and serum tau to predict poor outcome. (A–C) Correlations between serum tau and NSE. Rho coefficients and probability values are from Spearman correlation. The fitted lines were derived by local regression and are for visualization purposes. (D–F) Receiver operating characteristic (ROC) analyses for Cerebral Performance Categories (CPC) 1–2 vs CPC 3–5 at 6 months. Probability values are for area under the ROC curve (AUC) differences between NSE and tau. The combination of tau and NSE was not better than tau alone (AUC = 0.76 at 24 hours, 0.89 at 48 hours, and 0.91 at 72 hours).