Table 1.

Demographics

Characteristic	Value
No.	689
Age, yr	63.9 ± 12.4
Sex, M/F	558/131 (81%)
Time to ROSC, min	30.9 ± 22.5
Bystander CPR, No., yes/no	500/189 (73%)
CPC at 6 months, No., 1/2/3/4/5	304/43/27/8/307 (44%/6.2%/3.9%/1.2%/45%)
mRS at 6 months, No., 0/1/2/3/4/5/6	140/114/71/26/17/14/307 (20%/17%/10%/3.8%/2.5%/2%/45%)

Continuous data are given as mean ± standard deviation. Tau data were available in 667 patients at 24 hours (334 in TTM33 and 333 in TTM36), in 638 patients at 48 hours (313 in TTM33 and 325 in TTM36), and in 590 patients at 72 hours (289 in TTM33 and 301 in TTM36). There were no significant differences in age, sex, time to ROSC, bystander CPR, or CPC or mRS at 6 months between participants with tau data at 24 hours, 48 hours, or 72 hours.

Higher tau was associated with older age (p = 0.00013 for 24‐hour tau, p < 0.0001 for 48‐hour and 72‐hour tau), longer time to ROSC (p < 0.0001), and lack of bystander CPR (p = 0.0060 for 24‐h tau, p = 0.0038 for 48‐hour tau, p = 0.040 for 72‐hour tau). Tau at 72 hours was slightly higher in females than in males (median = 3.5, IQR = 1.7–54.7ng/l vs median = 2.6, IQR = 1.2–24.3ng/l, p = 0.043).

CPC = Cerebral Performance Categories; CPR = cardiopulmonary resuscitation; F = female; IQR = interquartile range; M = male; mRS = modified Rankin scale; ROSC = return of spontaneous circulation; TTM = Target Temperature Management.