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. Author manuscript; available in PMC: 2017 Dec 11.
Published in final edited form as: Cancer Lett. 2015 Nov 3;370(2):302–312. doi: 10.1016/j.canlet.2015.10.030

Figure 2.

Figure 2

Pedigrees of the families with FAN1 variants. Carrier status is depicted for all the cases in which germline DNA was available and tested. +/- indicates heterozygous carrier status. +/+ indicates wild-type. Probands are indicated with an arrow. Individuals shaded in black are affected with PC, while individuals shaded in grey are affected with a tumor other than PC. The ages of living family members and the ages of death (d.) for deceased individuals are indicated in years. Tumor types and ages at diagnoses are indicated in years. Other illnesses with ages in years at diagnosis (if known) are shown. NHL, non-Hodgkin's lymphoma; CLL, Chronic lymphocytic leukemia. Maternal and paternal ancestries are indicated.