Table 1.
Subject ID |
Sex | PMA at birth (weeks) | TP (μg/ml) | PMA at CSF sample (weeks) | Temporizing neurosurgical procedure | PMA at temporizing procedure (weeks) | VP shunt surgery PMA (weeks) |
---|---|---|---|---|---|---|---|
1 | M | 24.00 | 2369 | 26.86 | RES | 27.00 | 37.57 |
2 | F | 29.57 | 1745 | 30.29 | RES | 31.29 | 36.57 |
3 | F | 24.00 | 6072 | 26.86 | RES | 27.86 | 34.71 |
4 | M | 29.00 | 4564 | 31.14 | RES | 31.57 | 40.86 |
5 | M | 26.00 | 9596 | 27.43 | RES | 28.14 | 38.14 |
6 | M | 28.14 | 2606 | 28.71 | RES | 30.14 | 37.14 |
7 | F | 24.57 | 1270 | 28.00 | RES | 30.57 | 39.29 |
8 | M | 24.71 | 1869 | 30.57 | RES | 34.14 | 59.29 |
9 | M | 25.43 | 1420 | 27.57 | NAa | NA | NA |
10 | M | 25.43 | 2620 | 28.71 | RES | 31.00 | 53.57 |
11 | M | 25.86 | 1902 | 27.71 | RES | 28.14 | NAb |
12 | M | 25.29 | 3735 | 27.71 | RES | 28.00 | 40.00 |
13 | F | 29.57 | 2331 | 30.00 | RES | 31.29 | 36.57 |
14 | F | 24.00 | 4300 | 26.43 | RES | 27.00 | 37.57 |
PMA post-menstrual age, TP total protein, CSF cerebrospinal fluid, VP ventriculo-peritoneal, RES ventricular reservoir, NA not available
aSubject 9 expired after withdrawal of care by family
bSubject 11 developed a S. capitis RES infection 12 weeks after RES implantation and device tapping for cerebrospinal fluid removal (CSF). CSF samples prior to the 12-week sample were sterile on culture. After infection, the RES was removed and replaced with an external ventricular drain, which was later successfully weaned, and no shunt was implanted. Subject 10 underwent endoscopic third ventriculostomy with choroid plexus cauterization prior to VP shunt placement. Subject 1 had a shunt malfunction within 6 months of VP shunt implantation