Table 3.
Comparison of cerebrospinal fluid absolute and normalized concentrations of common chemokines in control and post-hemorrhagic hydrocephalus subjects
| Control mean (SD) |
PHH mean (SD) |
Mean difference | 95% confidence interval | p value | |
|---|---|---|---|---|---|
| XCL-1 (ng/ml) | 0.6680 (0.0833) | 0.5528 (0.1121) | − 0.1152 | − 0.0224 to − 0.2079 | 0.0176 |
| Normalized XCL-1 | 5.4E−5 (1.6E−5) | 2.19E−5 (1.1E−5) | − 3.3E−5 | − 1.76E−5 to − 4.8E−5 | 0.0002 |
| CCL-2 (pg/ml) | 9436 (5117) | 9535 (5089) | 99.45 | − 4622 to 4821 | n.s. |
| Normalized CCL-2 | 7.79E−4 (5.76E−4) | 4.16E−4 (4.08E−4) | − 3.62E−4 | − 8.47E−4 to 1.21E−4 | n.s. |
| CCL-3 (pg/ml) | 16.50 (11.02) | 360.0 (327.7) | 343.5 | 537.9–149.1 | 0.0018 |
| Normalized CCL-3 | 0.015 (0.0092) | 1.2E−5 (9.9E−6) | − 0.0146 | − 0.00658 to − 0.0227 | 0.0014 |
| CCL-19 (pg/ml) | 28.46 (45.15) | 410.8 (377.9) | 382.4 | 591.8–173.0 | 0.0011 |
| Normalized CCL-19 | 1.73E−6 (2.14E−6) | 1.41E−5(2.1E−5) | 1.23E−5 | 2.36E−5 to 9.96E−7 | 0.0345 |
| CXCL-10 (pg/ml) | 809.6 (776.6) | 1480 (742.6) | 670 | 1325–15.09 | 0.0454 |
| Normalized CXCL-10 | 5.9E−5 (5.8E−5) | 5.72E−5 (4.42E−5) | − 2.14E−6 | 4.32E-5 to − 4.75E-5 | n.s. |
| CXCL-11 (pg/ml) | 5.162 (10.68) | 5.15 (4.58) | − 8.7E−3 | 7.869 to − 7.886 | n.s. |
| Normalized CXCL-11 | 4.08E−7 (1.01E−6) | 1.38E−7 (8.01E−8) | − 2.71E−7 | 4.39E−7 to − 9.80E−7 | n.s. |
| CXCL-12 (ng/ml) | 0.5187 (0.5528) | 0.9930 (1.0002) | 0.4743 | 1.052 to − 0.1033 | n.s. |
| Normalized CXCL-12 | 4.5E−5 (5.3E−5) | 1.4E−5 (9.6E−6) | − 3.01E−5 | 2.01E-5 to − 7.5E−5 | n.s. |
SD standard deviation, PHH post-hemorrhagic hydrocephalus