Table 3.

Medical conditions associated with necrotizing fasciitis deaths in the United States, 2003–2013.

Condition	ICD-10 Codes	Necrotizing fasciitis- related deaths (%) N=9,871	Matched controls* (%) N=98,710	Matched OR (95% CI)
Diabetes mellitus	E10–E14	2,109 (21%)	10.316 (10%)	2.37 (2.25, 2.50)
Heart disease	I00–I99	3,301 (33%)	49,007 (50%)	0.49 (0.47, 0.51)
Renal failure	N17–N19	1,695 (17%)	8,223 (8%)	2.31 (2.18, 2.45)
Substance use	F10–F19	934 (9%)	12,076 (12%)	0.74 (0.69, 0.80)
Liver disease	K70–K77	617 (6%)	5,872 (6%)	1.06 (0.97, 1.15)
Obesity	E65–E68	519 (5%)	1,928 (2%)	2.83 (2.56, 3.13)

^*Each case of necrotizing fasciitis-related death was matched to 10 controls by age, sex, and race/ethnicity