TABLE.

Perineurioma Mutation and Clinical Summary of Patients Studied

Case	Mutation Found	Affected Nerve(s)	Age at Evaluation, yr	Gender	Symptom Duration, mo	Presenting Symptom	Pain	Sensory Loss	NIS
C1	TRAF7 p.L519P	Sciatic	14	M	18	Weakness and atrophy	N	Y	7
C2	Abnormal CGHa	Tibial	35	M	180	Weakness	N	Y	9.5
C3	TRAF7 p.S561R	Sciatic	12	F	6	Weakness	Y	Y	7
C4	TRAF7 p.S561R	Ulnar	13	F	24	Weakness	Y	Y	3.25
C5	None	Sciatic	30	M	78	Weakness	Y	N	22
C6	TRAF7 p.H521R	Brachial plexus	35	M	360	Weakness	N	Y	49
C7	TRAF7 p.S561R	Lumbosacral plexus	2	F	24	Weakness	N	Y	30
C8	TRAF7 p.L519P	Tibial	37	M	77	Weakness	N	Y	9.5
C9	TRAF7 p.L519P	Radial	30	F	48	Pain	Y	Y	6
C10	Abnormal CGHa	Radial	57	F	108	Weakness	N	Y	11
C11	TRAF7 p.H521R	Brachial plexus	12	F	48	Weakness	N	N	19
C12	TRAF7 p.S561R	Sciatic	7	M	60	Weakness	N	N	14
C13	None	Sciatic	34	M	48	Weakness	Y	Y	11.5
C14	TRAF7 p.H521R	Median	40	M	108	Weakness	Y	Y	9
C15	None	Peroneal	18	M	18	Weakness	N	Y	7
C16	None	Sciatic	31	M	156	Weakness and atrophy	Y	Y	12.25

^aSee Figure 2.

CGH = chromosomal genome hybridization; F = female; M = male; N = no; NIS = Neuropathy Impairment Score, which sums total motor, sensory, and reflex abnormalities¹²; Y = yes.