Table 1.
Markers used for the positive identification of pericytes in skeletal muscle and heart.
| Marker | Also known as | References (skeletal muscle) | References (heart) |
|---|---|---|---|
| CD10 | Neural endopeptidase | 1 | 1 |
| CD13 | Alanine aminopeptidase | 1 | 1 |
| CD29 | Integrin beta 1 | 2 | |
| CD34 | 3 | ||
| CD44 | Receptor for hyaluronic acid | 1,2,3 | 1,4 |
| CD73 | 5′nucleotidase, ecto | 1,2,3 | 1,4 |
| CD90 | Thy-1 | 1,2,3 | 1,4 |
| CD105 | Endoglin | 1,2,3 | 1,4 |
| CD108 | Sema L | 1 | 1,4 |
| CD109 | Platelet activation factor | 1 | 1 |
| CD140b | Platelet-derived growth factor beta (PDGFRβ) | 1,2,4 | 1,4 |
| CD140a | Platelet-derived growth factor beta (PDGFRα) | 5 | |
| CD146 | Melanoma cell adhesion molecule | 1,2,3,4 | 1,4 |
| CD164 | Sialomucin core protein 24 | 1 | 1 |
| CD166 | ALCAM | 1 | 1 |
| CD318 | CUB domain-containing protein 1 | 1 | 1 |
| CD340 | Human epidermal growth factor receptor 2 | 1 | 1 |
| CD349 | Frizzled-9 | 1 | 1 |
| NG2 | Neurol/glial antigen 2 | 1,2,4 | 1,4 |
| SM-MHC | Smooth muscle myosin heavy chain | 4 | |
| SSEA-4 | Stage-specific embryonic antigen-4 | 1 | 1 |
| STRO-1 | 5 | 5 | |
| HLA-CLI | Human leukocyte antigen class 1 | 1 | 1 |
| α-SMA | Alpha smooth muscle actin | 1,4 | 1,4 |
[References for table].
Crisan, M. et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 3, 301–313 (2008).
Dar, A. et al. Multipotent Vasculogenic Pericytes From Human Pluripotent Stem Cells Promote Recovery of Murine Ischemic Limb. Circulation 125, 87–99 (2012).
Avolio, E., Meloni, M., Spencer, H. L., Riu, F., Katare, R., Mangialardi, G., Oikawa, A., Rodriguez-Arabaolaza, I., Dang, Z., Mitchell, K., Reni, C., Alvino, V. V., Rowlinson, J., Livi, U., Cesselli, D., Angelini, G., Emanueli, C., Beltrami, A. P., & Madeddu, P. (2015). Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair. Circ Res, 116, e81–94.
Chen, C.-W., Corselli, M., Péault, B. & Huard, J. Human blood-vessel-derived stem cells for tissue repair and regeneration. J. Biomed. Biotechnol. 2012, 597,439–9 (2012).
Chen, W. C. W. et al. Human myocardial pericytes: multipotent mesodermal precursors exhibiting cardiac specificity. STEM CELLS 33, 557–573 (2015).
Psaltis, P. J., Harbuzariu, A., Delacroix, S., Holroyd, E. W. & Simari, R. D. Resident Vascular Progenitor Cells—Diverse Origins, Phenotype, and Function. J. of Cardiovasc. Trans. Res. 4, 161–176 (2010).