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. Author manuscript; available in PMC: 2018 Dec 10.
Published in final edited form as: Stat Med. 2017 Dec 10;36(28):4498–4502. doi: 10.1002/sim.7340

Table 1.

Values of the NRI using various cut points* comparing models with and without systolic blood pressure.

All Cases Non-cases
NRI 95% CI p NRI 95% CI P NRI 95% CI p
NRI>0 0.382 0.299 to 0.465 <0.0001 0.159 0.077 to 0.241 0.0001 0.223 0.210 to 0.235 <0.0001
4-Category 0.078 0.035 to 0.121 0.0004 0.084 0.041 to 0.127 0.0001 −0.006 −0.011 to −0.002 0.0019
3-Category 0.061 0.024 to 0.098 0.0013 0.066 0.029 to 0.103 0.0004 −0.006 −0.009 to −0.002 0.0027
2-Category 0.044 0.014 to 0.074 0.0036 0.048 0.019 to 0.078 0.0014 −0.004 −0.007 to −0.002 0.0010
NRI(p) 0.005 −0.020 to 0.030 0.69 −0.007 −0.031 to 0.017 0.56 0.012 0.008 to 0.016 <0.0001
*

Cut points for 8-year risk are 0.04, 0.06, and 0.08 for the 4-category NRI (corresponding to 10-year risk of 0.05, 0.075, and 0.10); 0.04 and 0.08 for the 3-category NRI; and 0.06 for the 2-category NRI. The observed 8-year incidence in the sample (p) is 0.023.