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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Top Magn Reson Imaging. 2017 Dec;26(6):251–258. doi: 10.1097/RMR.0000000000000145

Figure 5.

Figure 5

ASL assessment of response to antiangiogenic therapy in metastatic clear cell renal cell carcinoma. (A) Axial single shot fast spin echo image of the upper abdomen demonstrating a large metastatic lesion in the liver measuring 12.8 × 10.1 cm. (B) Concurrent axial pCASL acquisition demonstrates high perfusion level in the liver mass (arrowheads). (C) After two cycles of treatment with pazopanib, the mass decreased in size to 10.3 × 7.4 cm, just reaching the threshold for partial response (20% decrease). However, pCASL demonstrates nearly complete absence of tumor perfusion, more clearly illustrating the anti-angiogenic therapeutic effect.