Table 2. The mean serum levels of inflammatory modulating cytokines for age subgroups of the participants .
Age groups | Control (n = 50) | Case (n = 50) | Total (n = 100) | P -value | |
65 to 75 years | TNF-α (pg/mL) | 599.70 ± 89.68 | 521.06 ± 19.78 | 561.56 ± 82.40 | < 0.001 |
IL-1 (pg/mL) | 435.50 ± 50.32 | 326.06 ± 28.13 | 383.95 ± 75.07 | < 0.001 | |
IL-6 (pg/mL) | 412.80 ± 63.55 | 296.81 ± 44.35 | 365.98 ± 84.57 | < 0.001 | |
76 to 85 years | TNF-α (pg/mL) | 636.71 ± 87.93 | 481.75 ± 54.75 | 560.32 ± 84.67 | < 0.001 |
IL-1 (pg/mL) | 428.71 ± 61.82 | 328.70 ± 63.05 | 371.51 ± 62.78 | < 0.001 | |
IL-6 (pg/mL) | 468.75 ± 41.75 | 312.65 ± 51.25 | 353.86 ± 50.13 | < 0.001 | |
86 to 95 years | TNF-α (pg/mL) | 708.44 ± 111.96 | 495.64 ± 51.64 | 577.33 ± 108.83 | < 0.001 |
IL-1 (pg/mL) | 439.69 ± 54.64 | 268.86 ± 48.43 | 365.37 ± 53.10 | < 0.001 | |
IL-6 (pg/mL) | 469.25 ± 53.51 | 288.14 ± 40.87 | 369.25 ± 52.46 | < 0.001 |
TNF-α: tumor necrosis factor alpha; IL-1: interleukin 1; IL-6: interleukin 6