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. 2017 Dec 8;10:5817–5826. doi: 10.2147/OTT.S150456

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© 2017 Cui et al. This work is published and licensed by Dove Medical Press Limited

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The influence of the FAK inhibitor PF562271 on the expression of FAK, p-FAK, caspase 3, and iPLA₂.

Notes: Western blot analysis of caspase 3, cleaved caspase 3, and iPLA₂ in feeder cells and of FAK and p-FAK in receptor cells with the FAK inhibitor PF562271 (PF) added to the system. Each bar represents the mean ± SD of three independent experiments, ^*P<0.05 compared with the control group, ^#P<0.05 compared with the model group.

Abbreviations: FAK, focal adhesion kinase; p-FAK, phosphorylated FAK; iPLA₂, cytosolic calcium-independent phospholipase A₂; SD, standard deviation; VP-16, etoposide phosphate.