FIG. 6.
DOI restores firing ability in motoneuron with Ca PIC but no Na PIC. Motoneuron from acute spinal rat, recorded without nimodipine present, in same format as Fig. 5. A: motoneuron was unable to initiate action potentials or repetitive firing with slow current ramp. Note large Ca plateau. Normal size action potential was generated in response to antidromic stimulation (inset in A). B: without nimodipine, this motoneuron had a Ca PIC. C: DOI enabled repetitive firing with slow current ramps. D: amplitude of the total PIC was larger in DOI.