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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Cancer Res. 2017 Dec 1;77(23):6777–6787. doi: 10.1158/0008-5472.CAN-17-1296

Table 1.

Pre-diagnosis demographic characteristics of esophageal adenocarcinoma and squamous cell carcinoma cases and matched controls.

Adenocarcinoma Squamous Cell Carcinoma

Characteristic Cases
(n=81)
Matched Controls
(n=160a)
p Cases
(n=25)
Matched Controls (n=50) p
Sexb (%) 1.00c 1.00c

 Women 7.4 7.5 60.0 60.0
 Men 92.6 92.5 40.0 40.0

Ageb (mean ± SD) 68.0 ± 6.7 68.0 ± 6.6 0.95d 66.6 ± 6.5 66.8 ± 6.4 0.83d

Raceb (%) 1.00c 1.00c

 White 97.5 97.5 84.0 84.0
 Other 2.5 2.5 16.0 16.0

BMIe (%) 0.38c,f 0.07c,f

 Normal weight 22.2 21.9 52.0 38.0
 Overweight 50.6 55.6 36.0 32.0
 Obese 21.0 13.8 4.0 26.0
 Missing 6.2 8.8 8.0 4.0

Smoking (%) 0.12c 0.36c

 Never 25.9 36.9 36.0 44.0
 Current 9.9 5.0 16.0 6.0
 Former 64.2 58.1 48.0 50.0

Alcohol drinkingg (%) 0.20c,f 0.004c,f

 Never 21.0 25.6 24.0 26.0
 Moderate 51.9 53.1 32.0 54.0
 Heavy 17.3 9.4 36.0 6.0
 Missing 9.9 11.9 8.0 14.0

Fruit and vegetable intakeh (%) 0.85c,f 1.00c,f

 Low 44.4 42.5 48.0 48.0
 High 43.2 45.6 40.0 38.0
 Missing 12.3 11.9 12.0 14.0
a

There were two incomplete case sets (1 case: 1 control).

b

Sex, age, and race were matching factors.

c

Differences between cases and controls were detected using the Chi-squared test.

d

Differences between cases and controls were detected using the Wilcoxon rank-sum test .

e

Normal-weight: BMI < 25 kg/m2; Overweight: 25 ≤ BMI < 30 kg/m2; Obese: BMI ≥ 30 kg/m2.

f

P-value determined after exclusion of those missing the variable.

g

Moderate drinker: >0 but ≤1 drinks/day for women, and >0 but ≤2 drinks/day for men; Heavy drinker: >1 drinks/day for women, and >2 drinks/day for men.

h

Low and high intake groups reflect participants below or above cohort-specific median of servings of fruit and vegetables/day. CPS-II median=4.62 servings/day; PLCO median=6.10 servings/day.