Table 5. Accuracy of main prediction methods in analyses of height in an African cohort.

Model	Weights associated to each predictor		Adjusted R2	P-value for improvement over simpler model
	European PRS	African PRS
EUR	0.164		0.02618	<10-11
AFR		0.106	0.01074	<10-5
AFR+ANC		0.124	0.01331	0.01
EUR+AFR	0.155	0.092	0.03397	<10-3
EUR+AFR+ANC	0.150	0.102	0.03443	0.17
EUR-AFR-meta	0.151	0.027	0.03158	NA

We report adjusted R² on the observed scale for each of the 5 main prediction methods, as well as EUR-AFR-meta. P-values are from likelihood ratio tests comparing models EUR and AFR to the null model, model AFR+ANC to AFR, model EUR+AFR to EUR, and EUR+LAT+ANC to EUR+AFR. For the EUR model we used R_LD²=0.2 and P_T=10^-3, for AFR we used R_LD²=0.8 and P_T=0.05 and for EUR-AFR-meta we used R_LD²=0.2and P_T=10^-6. We also report normalized weights, defined as the mixing weight ${\widehat{\alpha }}_k$ (see Methods) multiplied by the standard deviation of the PRS.