Table 1.
The differences of survival patterns for each variable analyzed by log-rank test.
| Variable | Number (%) | 3-M survival (%) | 6-M survival (%) | 1-Y Survival (%) | p-value |
|---|---|---|---|---|---|
| Total | 505 (100) | 64.5 | 44.7 | 25.3 | – |
| Gender | |||||
| Female | 177 (35.1) | 69.9 | 52.7 | 35.9 | |
| Male | 328 (64.9) | 61.7 | 40.3 | 19.6 | 0.008* |
| Age of bone metastasis | |||||
| < 60 year | 264 (52.3) | 64.5 | 44.2 | 25.6 | |
| ≥ 60 year | 241 (47.7) | 64.5 | 45.1 | 25.0 | 0.892 |
| ECOG score | |||||
| ECOG 0–2 | 364 (72.1) | 66.4 | 47.4 | 26.3 | |
| ECOG 3–4 | 141 (27.9) | 59.7 | 37.6 | 22.8 | 0.026* |
| Histology diagnosis | |||||
| Small cell | 30 (5.9) | 62.3 | 32.0 | 10.7 | |
| Non-small cell | 475 (94.1) | 64.7 | 45.4 | 26.0 | 0.098* |
| Type of SREs | |||||
| Other symptoms | 427 (84.5) | 64.6 | 46.0 | 25.4 | |
| Parapariasis | 78 (15.5) | 63.9 | 36.8 | 25.0 | 0.407 |
| Site of bone metastasis | |||||
| Single | 150 (29.7) | 64.7 | 48.6 | 26.0 | |
| Multiple | 355 (70.3) | 64.5 | 43.0 | 25.0 | 0.692 |
| Extraosseous metastasis | |||||
| No | 354 (70.1) | 67.9 | 46.6 | 25.4 | |
| Yes | 151 (29.9) | 56.7 | 40.1 | 25.1 | 0.286 |
| Creatinine level | |||||
| < 1.4 mg/mL | 333 (87.9) | 66.6 | 47.9 | 28.5 | |
| ≥ 1.4 mg/mL | 46 (12.1) | 58.4 | 40.4 | 17.9 | 0.311 |
| Hematocrit level | |||||
| < 34% | 175 (45.7) | 69.0 | 48.5 | 29.9 | |
| ≥ 34% | 208 (54.3) | 64.4 | 46.2 | 24.5 | 0.243 |
| Albumin level | |||||
| ≥ 3.4 mg/mL | 155 (30.7) | 60.9 | 44.3 | 28.7 | |
| < 3.4 mg/mL | 193 (38.2) | 72.4 | 51.7 | 26.2 | 0.399 |
| AST level | |||||
| < 60 mg/mL | 315 (62.4) | 75.8 | 48.3 | 28.7 | |
| ≥ 60 mg/mL | 34 (6.7) | 76.5 | 41.2 | 20.6 | 0.231 |
| ALT level | |||||
| < 31 mg/mL | 263 (52.1) | 67.7 | 49.0 | 28.9 | |
| ≥ 31 mg/mL | 87 (17.2) | 61.8 | 42.9 | 24.2 | 0.455 |
| Serum calcium level | |||||
| < 9.2 mg/mL | 161 (31.9) | 60.5 | 47.7 | 29.6 | |
| ≥ 9.2 mg/mL | 141 (27.9) | 65.2 | 46.9 | 24.0 | 0.268 |