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. Author manuscript; available in PMC: 2017 Dec 12.
Published in final edited form as: J Am Chem Soc. 2016 Jul 1;138(27):8497–8504. doi: 10.1021/jacs.6b03599

Figure 2.

Figure 2

KRAS gene sequence studied herein. The target oligonucleotides were designed such that their middle base was the middle base of either codon 12 or codon 13 (underlined bases). The length of the targets was varied for the evaluation studies performed with targets centered on codon 13 (13-, 17-, 21-mer). The target was a 17-mer for the codon 12-based studies.