Table II.

Simulation results for XCI escape gene analysis. Mean sensitivity, specificity, and accuracy are calculated across the 100 replications and defined with respect to identifying escape genes based upon PP_jg > 0. Performance measures for discordant genes under the informative prior are based upon the subset of 10 genes with inaccurate prior definitions.

		Flat Prior			Informative Prior			Informative Prior with Errors
								Overall			Discordant Genes
Ng	mI	Acc	Sens	Spec	Acc	Sens	Spec	Acc	Sens	Spec	Acc	Sens	Spec
10	0.30	0.48	0.82	0.48	0.72	0.69	0.69	0.67	0.64	0.68	0.20	0.20	0.19
	0.20	0.72	0.80	0.72	0.81	0.80	0.80	0.77	0.77	0.77	0.44	0.56	0.31
	0.10	0.75	0.93	0.75	0.86	0.84	0.84	0.83	0.90	0.82	0.66	0.79	0.52
20	0.30	0.64	0.75	0.64	0.77	0.87	0.75	0.73	0.68	0.74	0.28	0.36	0.21
	0.20	0.76	0.88	0.76	0.86	0.94	0.85	0.82	0.84	0.82	0.48	0.69	0.26
	0.10	0.86	0.97	0.86	0.92	0.98	0.90	0.90	0.96	0.89	0.76	0.93	0.59
30	0.30	0.68	0.77	0.76	0.78	0.88	0.76	0.75	0.69	0.75	0.26	0.35	0.16
	0.20	0.80	0.92	0.92	0.87	0.96	0.86	0.84	0.89	0.83	0.50	0.75	0.25
	0.10	0.90	0.98	0.98	0.94	0.98	0.93	0.92	0.97	0.91	0.83	0.95	0.72