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. Author manuscript; available in PMC: 2018 Nov 28.
Published in final edited form as: J Am Coll Cardiol. 2017 Nov 28;70(21):2663–2673. doi: 10.1016/j.jacc.2017.09.1089

Table 3.

Unadjusted Cox Proportional Hazards Regression Analysis of Predictors of Death among 1953 Children with Dilated Cardiomyopathy not Undergoing Heart Transplantation.

N Hazard ratio (95% CI) p
Age, year 1953 1.02 (1.003, 1.04) 0.02
Male 1953 1.09 (0.87, 1.38) 0.45
Race 1917 0.13
 White Reference
 Black 1.35 (1.02, 1.78)
 Hispanic 0.94 (0.67, 1.31)
 Other 0.93 (0.55, 1.55)
Era of diagnosis 1953 <0.001
 Early cohort (1990–1999) 1.59 (1.22, 2.09)
 Late cohort (2000–2010) Reference
Type 1952 <0.001
 Idiopathic Reference
 Myocarditis 0.48 (0.30, 0.76)
 Neuromuscular disease 1.86 (1.36, 2.54)
 Familial 0.42 (0.19, 0.94)
 Error of metabolism 1.39 (0.76, 2.55)
 Malformation syndrome 2.09 (0.78, 5.61)
Heart failure at diagnosis 1943 1.80 (1.37, 2.37) <0.001
Diuretic therapy 1890 1.00 (0.73, 1.38) 0.67
Family history of sudden death 1121 1.14 (0.71, 1.81) 0.51
LVEDD z-score 1527 1.04 (0.99, 1.09) 0.12
LVESD§ z-score 1338 1.07 (1.01, 1.12) 0.01
LV** fractional shortening z-score 1580 0.93 (0.89, 0.96) <0.001
LV posterior wall thickness z-score 1235 0.94 (0.89, 1.01) 0.08
Septal thickness z-score 1127 0.91 (0.84, 0.99) 0.04
LV mass z-score 1217 1.01 (0.95, 1.06) 0.86

LVEDD, left ventricular end-diastolic dimension

§

LVESD, left ventricular end-systolic dimension

**

LV, left ventricular