Skip to main content
. Author manuscript; available in PMC: 2018 Dec 12.
Published in final edited form as: J Am Coll Cardiol. 2017 Dec 12;70(23):2893–2905. doi: 10.1016/j.jacc.2017.10.014

Figure 1. EPL mitigates structural remodeling.

Figure 1

(A) Echocardiographically measured atrial areas adjusted by body weight at 5 different time points from SP-treated (N=15), EPL-treated (N=19) and sham-operated (N=6) groups. *p < 0.05 versus sham; #p < 0.05 vs EPL-treated group. LA=left atrium; RA=right atrium. (B) Mitral regurgitation (MR) at 5 different time points. (C) Atrial tissue weight adjusted by body weight at the end of the experiment. (D) Atrial areas obtained by direct measurement of the tissue at the end of experiment. (E) Single isolated cell length and width in Sham (N/n=4/192), SP-treated (N/n=4/144) and EPL-treated groups (N/n=5/244). *P<0.05, **P<0.01, ****P<0.0001. N = number of animals, n = number of cells.