Skip to main content
. Author manuscript; available in PMC: 2018 Dec 12.
Published in final edited form as: J Am Coll Cardiol. 2017 Dec 12;70(23):2893–2905. doi: 10.1016/j.jacc.2017.10.014

Figure 4. EPL does not reduce ion channel remodeling during AF progression.

Figure 4

(A) Left, Inward rectifier potassium (IK1) current-voltage relationships for LA cells from SP treated (N/n=3/7) and EPL-treated (N/n=5/14) animals. Right, IK1 current-voltage relationships for RA cells from for SP-treated (N/n=2/7) and EPL-treated (N/n=5/13) animals. (B) Left, current-ICaL voltage relationships for LA from SP treated (N/n=4/11) and EPL-treated (N/n=5/24) animals. Right, current-voltage relationships for RA from SP treated (N/n=4/17) and EPL-treated ICaL (N/n=5/26) animals. Two-way ANOVA with post hoc Bonferroni’s test. (C) Western blots for Kir2.3 (left) and Cav1.2 (right) in LA tissue lysate. Protein expression of both ion channel types was similar for SP-treated (N=4) and EPL-treated groups (N=5).