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. Author manuscript; available in PMC: 2018 Dec 12.
Published in final edited form as: J Am Coll Cardiol. 2017 Dec 12;70(23):2893–2905. doi: 10.1016/j.jacc.2017.10.014

Figure 5. EPL reduces AF wave propagation complexity.

Figure 5

(A) Representative 3-dimensional plots of spatial trajectories of rotors at consecutive movie frame numbers (500 μm2 pixels, 600 frames/s) for SP-treated (left) and EPL-treated (right) hearts. Note the reduced complexity in the trajectories of two rotors recorded from persistent AF hearts in the EPL treated compared with the SP treated hearts. (B and C) Quantification of lifespan (B) and trajectory length per rotation (C) of rotors recorded in optical mapping experiments from the PLA, LA and RA of SP-treated and EPL-treated hearts. Rotor lifespans were similar, but rotor trajectories were significantly shorter and less complex for EPL-treated than SP-treated hearts.