Table 3. Cytotoxicity of iridoid valepotriates against HepG2, HeLa and MDA-MB-231 cells and HUVECs.

Compound	Cancer Cell Lines (IC50, μM, n = 3)
	HepG2	HeLa	MDA-MB-231	HUVEC
V	25.4 ± 0.6	37.1 ± 1.1	30.5 ± 0.5	97.5
AV	30.4 ± 0.7	42.3 ± 1.3	37.5 ± 0.5	92.2
BAV	48.5 ± 2.1	50.3 ± 0.8	60.3 ± 1.8	>100
VD	50.5 ± 1.9	60.1 ± 2.1	75.1 ± 1.9	89.1 ± 1.9
AVD	62.4 ± 0.9	>100	80.2 ± 1.4	>100
BAVD	>100	>100	>100	>100
CP	15.2 ± 1.2	12.7 ± 0.6	13.1 ± 1.1	95.6 ± 1.3