Table 2. Simulation outputs (mean ± standard deviation) from model parameterizations with optimal fits to experimental results.
| % Glucan Coverage | Min DPedge | Singlet Fraction | Equivalent Radius (nm) | Exposure Site Density (μm-2) |
|---|---|---|---|---|
| 5 | 10 | 0.64 ± 0.23 | 9.4 ± 2.1 | 6.8 ± 3.1 |
| 10 | 19 | 0.66 ± 0.21 | 9.3 ± 1.9 | 7.1 ± 2.9 |
| 15 | 25 | 0.66 ± 0.17 | 9.3 ± 1.5 | 7.1 ± 3.1 |
| 20 | 32 | 0.63 ± 0.22 | 9.5 ± 1.7 | 6.9 ± 2.8 |
| 5 | 11 | 0.63 ± 0.09 | 24.0 ± 1.5 | 27.8 ± 5.7 |
| 10 | 21 | 0.63 ± 0.09 | 23.9 ± 1.5 | 28.1 ± 6.4 |
| 15 | 29 | 0.63 ± 0.09 | 23.9 ± 1.4 | 28.2 ± 5.9 |
| 20 | 36 | 0.63 ± 0.10 | 23.8 ± 1.2 | 28.9 ± 6.3 |
All results shown correspond to simulations conducted at a representative glucan fibril width of 50 nm, and at values of Pedge associated with the minimum D for the given percent glucan coverage and treated condition. The top half of the table is untreated results, while the bottom half is caspofungin-treated results.