Table 2.
Linear Mixed Model Assessing the Interaction Between Aβ Status and Time on the PACC and CAT
| Model 1: CAT, covary PACC |
||||
|---|---|---|---|---|
| b | SE | t | P | |
| Intercept | 0.06 | 0.07 | 0.83 | .408 |
| Time | −0.07 | 0.20 | −4.76 | <.001 |
| Aβ+ | 0.11 | 0.11 | 0.97 | .332 |
| Age | −0.03 | 0.01 | −3.44 | <.001 |
| Education | 0.10 | 0.02 | 6.38 | <.001 |
| Sex (male) | −0.32 | 0.10 | −3.36 | <.001 |
| PACC | 0.28 | 0.04 | 6.56 | <.001 |
| Aβ+ × PACC | 0.03 | 0.07 | 0.42 | .672 |
| Aβ+ × time | −0.09 | 0.02 | −3.74 | <.001 |
| Age × time | −0.00 | 0.00 | −1.54 | .123 |
| Education × time | 0.00 | 0.00 | −0.25 | .805 |
| Sex × time | 0.02 | 0.02 | 1.01 | .322 |
Abbreviations: CAT, category fluency; PACC, preclinical Alzheimer's cognitive composite; SE, standard error.
NOTE. Age is centered at 75 years, and education is centered at 16 years.