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. 2017 Dec 12;12(12):e0189488. doi: 10.1371/journal.pone.0189488

Fig 3. Plot versus criterion value curves for the post-transplant 1 month pp65-ELISPOT and IE-1-ELISPOT assay for predicting CMV DNAemia.

Fig 3

The X-axis shows the cut-off spots/200,000 cells and the Y-axis shows the percentage of CMV DNAemia development. The sensitivity and specificity of pp65-ELISPOT at post-transplant 1 month for predicting CMV DNAemia were 70.0% (95% CI: 34.8–93.3) and 72.2% (95% CI: 60.4–82.1%) with a cut-off value of ≤ 30 spots/200,000 cells. IE-1-ELISPOT showed a sensitivity of 90.0% (95% CI: 55.5–99.7%) and a specificity of 54.7% (95% CI: 42.7–66.2%) to predict CMV DNAemia with a cut-off value of ≤ 10 spots/200,000 cells.