Table 4. Cox regression analysis of 5-year mortality in the older age group.

	Univariable		Multivariable
	HR (95% CI)	p-value	HR (95% CI)	p-value
Sex (men)	1.05 (0.70–1.57)	0.833	1.13 (0.74–1.71)	0.573
Hypertension	1.00 (0.62–1.61)	0.983
Diabetes	1.07 (0.72–1.58)	0.750
Hyperlipidemia	0.72 (0.37–1.44)	0.356
Smoking	1.30 (0.88–1.91)	0.189
Pulse pressure (mmHg)	1.00 (0.99–1.01)	0.555
Total cholesterol (mmol/L)	0.97 (0.79–1.20)	0.805
Triglyceride (mmol/L)	0.67 (0.48–0.93)	0.018	0.79 (0.58–1.10)	0.160
HDL (mmol/L)	0.90 (0.53–1.53)	0.699
LDL (mmol/L)	1.00 (0.82–1.22)	0.979
Serum creatinine (μmol/L)	1.39 (1.20–1.61)	<0.001	1.30 (1.12–1.50)	<0.001
Initial NIHSS score
0–2	1		1
3–5	2.91 (1.53–5.52)	0.001	3.59 (1.86–6.95)	<0.001
≥6	5.14 (2.92–9.04)	<0.001	5.36 (2.97–9.66)	<0.001
Previous antithrombotics	0.83 (0.39–1.80)	0.644
Previous statin	0.88 (0.32–2.39)	0.799
Severe WMH	1.55 (1.03–2.35)	0.036	1.75 (1.15–2.65)	0.008

Data are expressed as the hazard ratio (95% CI);

HDL, high density lipoprotein; LDL, Low density lipoprotein; NIHSS, National Institute of Health Stroke Scale; WMH, white matter hyperintensity.