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. Author manuscript; available in PMC: 2017 Dec 12.
Published in final edited form as: Neurotoxicology. 2016 Oct 6;60:161–170. doi: 10.1016/j.neuro.2016.10.003

Figure 3.

Figure 3

Differential sensitivity of recombinant α1β2γ2S and α6β2γ2S GABAA receptors to niflumic acid (NA). A, Whole cell currents were recorded from oocytes expressing α1β2γ2S (Top) or α6β2γ2S (Bottom) in response to 5 or 1 μM GABA, respectively, at a holding potential of −60 mV in the absence and presence of 500 μM NA. B, Comparison of effects of NA on IGABA on the two subtype receptors (n = 3 – 4). The asterisk (*) indicates a significant difference between control and NA treatment (p≤0.05). The number sign (#) indicates a significant difference between α1β2γ2S and α6β2γ2S containing receptors (p≤0.05).