Table 1.

Summary of cell migratory responses divided by chemokine type (intermediate vs. end agonist), cell type (BMDCs and neutrophils, WT and GRK3-deficient), chemoattractant (CCL19, CXCL12, C5a), and source input (stable v. continuous rise, homogeneous, presoak v. immediate).

Chemokine	Cell Type	Migratory Persistence Up Spatial Gradient		Directional Path of Early Migration	Directional Path of Persistent Migration
		Stable	Cont. Rise	Homogenous	Presoak	Immediate
CCL19	Mature DCs WT	None (Fig 1)	Directed (Fig 2)	Random (S. Fig 12)	Random (Fig 5)	Up Spatial Gradient (Fig 5)
CCL19	Mature DCs Grk3−/−	Directed (Fig 3)	Directed (Fig 3)	Random (Fig 6)	Up Spatial Gradient (Fig 6)	–
CXCL12	Mature DCs WT	None (Fig 4)	Directed (Fig 4)	–	–	–
CXCL12	Neutrophils WT	None (Fig 4)	Directed (Fig 4)	Random (S. Fig 12)	Random (Fig 5)	Up Spatial Gradient (Fig 5)
CXCL12	Neutrophils Grk3−/−	–	–	Random (Fig 6)	Up Spatial Gradient (Fig 6)	–
C5a	Immature DCs WT	Directed (Fig 4)	Directed (Fig 4)	–	–	–
C5a	Neutrophils WT	Directed (Fig 4)	Directed (Fig 4)	Random (S. Fig 12)	Up Spatial Gradient (Fig 5)	Up Spatial Gradient (Fig 5)