Table 3.
Primary tumor versus plasma at the time of diagnosis | ||||
---|---|---|---|---|
Patient | Disease | Tumor tissue DNA mutations detected in plasma samples | Plasma sample DNA mutations not detected in tumor tissues | Cancer cells in tumor |
1 | colon AC | 60% (3/5) | 79% (11/14) | 50% |
2 | colon AC | 0% (0/5) | 100% (5/5) | 70% |
3 | colon AC | 0% (0/1) | 100% (13/13) | 90% |
4 | colon AC | 75% (3/4) | 77% (10/13) | 70% |
5 | colon AC | 100% (3/3) | 0% (0/3) | 90% |
average | 47% | 71.2% | 74% | |
6 | PDAC | 25% (1/4) | 92% (11/12) | 30% |
7 | PDAC | 33% (1/3) | 89% (8/9) | 40% |
8 | PDAC | 33% (1/3) | 86% (6/7) | 50% |
9 | PDAC | 0% (0/3) | 100% (8/8) | 50% |
10 | PDAC | 50% (3/6) | 25% (1/4) | 40% |
average | 28.2% | 78.4% | 42% |
AC= adenocarcinoma; PDAC= pancreatic ductal adenocarcinoma