TABLE 1.

Clinical features of patients with CAPOS syndrome

	Nicolaides et al. (1996)			Demos et al. (2014)							Rosewich et al. (2014)	Heimer et al. (2015)			Potic et al. (2015)				Maas et al. (2016)				Current cases 2017
Case	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Demographics
Gender	M	F	F	F	M	M	M	F	F	M	M	F	M	F	M	M	F	M	F	F	M	F	M	F	M
Age of onset	16 m	18 m	9 m	5 y	9 m	18 m	6 m	3 y	1 y	3 y	20 m	2 y	9 m	4 y	4 y	3 y	4 y	4 y	1 y	4 y	3 y	3 y	22 m	18 m	9 m
Number of episodes	3	1	1	1	3	1	2	3	3	2	2	2	2	2	1	1	2	1	2	2	1	3	3	6	2
Ethnicity	British			French Canadian				British			German	Israeli			Slavic				Dutch				Mixed European
Symptoms
Cerebellar ataxia	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Areflexia	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Hearing loss	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Optic atrophy	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Pes cavus	+	+					+								+			+				+	+	+	+
Dysarthria	+			+							+						+	+		+		+	+	+
Dysphagia				+	+			+			+											+
Hypotonia	+		+				+	+	+	+	+	+	+				+	+	+	+	+	+	+	+	+
Lethargy	+			+	+			+		+	+		+		+	+	+	+	+	+				+
Strabismus					+	+	+		+		+	+		+					+
Nystagmus	+	+	+	+	+	+	+								+	+	+	+						+	+
Dystonia							+				+									+	+
Autism									+	+											+
Anxiety									+	+													+	+
LV enlargement				+	+
Full CAPOS	+	+					+								+			+				+	+	+	+