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. 2017 Dec 12;9:62. doi: 10.1186/s13321-017-0251-x

Table 2.

Possible structures with bioisosteric replacements found using BoBER

Replacement number Original fragment Bioisostere found by BoBER Similar bioisostere found by SwissBioisostere
1 graphic file with name 13321_2017_251_Figb_HTML.gif graphic file with name 13321_2017_251_Figc_HTML.gif graphic file with name 13321_2017_251_Figd_HTML.gif
2 graphic file with name 13321_2017_251_Fige_HTML.gif graphic file with name 13321_2017_251_Figf_HTML.gif graphic file with name 13321_2017_251_Figg_HTML.gif
3 graphic file with name 13321_2017_251_Figh_HTML.gif graphic file with name 13321_2017_251_Figi_HTML.gif No similar

Original join atoms are shown, however in 2 and 3 they were ignored during the procedure, as per usage of the Loose filtering option