Table 2.
Genes, which significantly increased expression across all three regions in aged animals from both the Illumina and Ion Proton data.
| Gene symbol | Gene Name | Immune related |
|---|---|---|
| C3 | Complement component 3 | x |
| Card11 | Caspase recruitment domain family, member 11 | x |
| Cd4 | Cd4 molecule | x |
| Cd74 | Cd74 molecule, major histocompatibility complex, class II invariant chain | x |
| Cdh1 | Cadherin 1 | |
| Cdh23 | Cadherin 23 (otocadherin) | |
| Csf1r | Colony stimulating factor 1 receptor | x |
| Ctss | Cathepsin S | x |
| Ctsz | Cathepsin Z | |
| Cx3cr1 | Chemokine (C-X3-C motif) receptor 1 | x |
| Fcgr2b | Fc fragment of IgG, low affinity IIb, receptor (CD32) | x |
| Gfap | Glial fibrillary acidic protein | x |
| Gpr183 | G protein-coupled receptor 183 | x |
| Gpr84 | G protein-coupled receptor 84 | x |
| Itgb2 | Integrin beta 2 | x |
| Ncf1 | Neutrophil cytosolic factor 1 | x |
| Nckap1l | NCK associated protein 1 like | x |
| Npc2 | Niemann-Pick disease, type C2 | |
| Pcdhb4 | protocadherin beta 4 | |
| Pld4 | Phospholipase D family, member 4 | |
| Slc14a1 | Solute carrier family 14 (urea transporter), member 1 | |
| Trem2 | Triggering receptor expressed on myeloid cells 2 | x |
| Bpifb4 | BPI Fold Containing Family B, Member 4 | |
| Wdfy4 | WDFY Family Member 4 |
Genes that are related to immune function are indicated.