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. 2017 Dec 12;7:17448. doi: 10.1038/s41598-017-17738-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Tactile Braille training induces grey matter volume increases in the peripheral early visual cortex. (a) Grey matter (GM) volume changes in the experimental group, following the tactile Braille training. (b) Individual subjects’ GM volume changes in the early visual cluster depicted in (a). (c) The results of ROI analysis in the early visual cortex. Thresholds: (a) false discovery rate of q < 0.05, cluster extent threshold of p < 0.05. (c) ***p < 0.001; *p < 0.05. The dotted line denotes a time x group interaction. Error bars represent standard error of the mean.