Table 1.

Summary of ExSSO calculation results^a.

TMD	# of residues	# of restraintsb	Avg. pairwise RMSD of the ensemble (Å)	RMSD from known structure (Å)c
Fas	22	13	4.5	1.5
gp41	34	18	2.8	2.1
M2	23	11	3.8	0.8
MCU	17	9	4.2	1.3

^aMore details in Supplementary Table 2.

^bNOE-derived inter-protomer restrains.

^cBackbone Cα difference between the best model (with the smallest ∆ from ExSSO) and the deposited NMR structure.