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. 2017 Dec 12;7:17419. doi: 10.1038/s41598-017-17232-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Time-dependent killing of exponential phase cultures of S. aureus SH1000 by γ-ACT and comparator agents at 4XMIC. The dotted line corresponds to a 3 log₁₀ reduction in CFU/ml relative to cell density at time 0, and represents the threshold at which an antibiotic is considered to exhibit bactericidal activity. Values shown are the means of at least three independent experiments, with error bars representing standard deviations from the mean.

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