Table 2.
The results of desensitization in the two groups at 32 week of the study entry.
| Characteristics | Group | p value | |
|---|---|---|---|
| OIT (N = 10) | Untreated (N = 6) | ||
| Passed DBPCFC | 10/10 | 0/6 | <0.001 |
| SCD of CMP at DBPCFC (mg) | |||
| 0 | 0 | 5 | <0.001 |
| 43 | 0 | 0 | |
| 130 | 0 | 1 | |
| 303 | 0 | 0 | |
| 650 | 0 | 0 | |
| 1340 | 0 | 0 | |
| 2080 | 10 | 0 | |
| Grade of allergic reaction at DBPCFC # | |||
| 0 | 10 | 0 | <0.001 |
| 1 | 0 | 3 | |
| 2 | 0 | 3 | |
| 3 | 0 | 0 | |
| 4 | 0 | 0 | |
| Passed fresh CM OFC | 7/10 | 0/6 | 0.01136 |
| SCD of CM at OFC (mL) | |||
| 0 | 0 | 6 | 0.006 |
| 15 | 0 | 0 | |
| 45 | 0 | 0 | |
| 105 | 3 | 0 | |
| 200 | 7 | 0 | |
| Grade of allergic reaction at DBPCFC # | |||
| 0 | 7 | 0 | 0.075 |
| 1 | 0 | 0 | |
| 2 | 1 | 6 | |
| 3 | 2 | 0 | |
| 4 | 0 | 0 | |
#Grade of anaphylaxis according to Sampson’s grading score24 OIT: oral immunotherapy, SCD: successfully consumed dose, CMP: cow’s milk protein, DBPCFC: double-blind placebo controlled food challenge, CM: cow’s milk, OFC: open food challenge, IQR: interquartile range, CS: casein, β-lact: β-lactoglobulin, α-lact: α-lactoalbumin.