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. 2017 Dec 12;7:17453. doi: 10.1038/s41598-017-16730-6

Table 6.

Averages of adverse reactions and treatments per dose per child in the escalation phase (at hospital), and maintenance phase of oral immunotherapy.

Phase Total Grade 1# Grade 2# Grade 3# Grade 4#
Escalation (401 total doses) 0.012 0.003 0.007 0 0
Maintenance (1414 total doses) 0.028 0.004 0.021 0.002 0
Phase Anti- histamines Nebulized epinephrine Nebulized β 2 agonists Oral steroids Intravenous steroids Epinephrine injections
Escalation 0.020 0.039 0 0 0 0
Maintenance 0 0 0.013 0.013 0 0

Reactions per dose per child. Each data express averages of reactions and treatments per dose per child. #Grade of anaphylaxis according to Sampson’s grading score24.