Table 3.
Subgroup analysis for the incidence of CA-AKI on the baseline chloride level depending on serum creatinine level [‘Normal Cr group’ (n = 12,280) and ‘Slightly increased Cr group (n = 808)].
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| RR (95% CI) | P-value | RR (95% CI) | P-value | |
| Normal Cr group (n = 12,280) | ||||
| Normochloremia | Reference | Reference | ||
| Hypochloremia | 1.347 (1.086–1.671) | 0.007 | 1.314 (1.550–1.636) | 0.015 |
| Hyperchloremia | 2.356 (1.419–3.913) | 0.001 | 1.360 (0.799–2.315) | 0.257 |
| Slightly increased Cr group (n = 808) | ||||
| Normochloremia | Reference | Reference | ||
| Hypochloremia | 1.781 (1.048–3.027) | 0.033 | 1.641 (0.940–2.866) | 0.082 |
| Hyperchloremia | 2.303 (0.912–5.819) | 0.078 | 2.322 (0.872–6.186) | 0.092 |
Abbreviations; CA-AKI, contrast-associated acute kidney injury; RR, relative risk; CI, confidence interval; Cr, creatinine.
Adjusted for age, sex, admission status, comorbidity diseases including DM, hypertension, coronary artery disease, and heart failure, serum creatinine level, serum BUN level, serum tCO2.
Normal Cr group; patients who had a serum Cr level of less than 1.2 mg/dL.
Slightly increased Cr group; patients who had 1.2 ≤ serum Cr levels < 2.0 mg/dL.
Hypochloremia; chloride level less than 98 mEq/L at baseline.
Normochloremia; chloride level between 98 to 110 mEq/L at baseline.
Hyperchloremia; chloride level over 110 mEq/L at baseline.