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. 2017 Dec 12;7:17413. doi: 10.1038/s41598-017-17660-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Minimum pH versus frequency of intake taken at a time of 60 days, where each line corresponds to a different total amount of glucose as indicated in the legend. From top to bottom, the curves correspond to total amounts of 10 g/L/d (○), 12.5 g/L/d (◊), 15 g/L/d (□), 17.5 g/L/d (▽), 20 g/L/d (◁), 22.5 g/L/d (▷), and 25 g/L/d (△). Markers are coloured according to $N_{A} / N_{t o t a l}$ with N _A the number of aciduric (A) particles and N _total the total number of particles of either type, with red for high values and green for low values, and the line pH = 5.5 below which enamel dissolution is expected to occur has been highlighted. Sample size n = 5 per point and standard errors shown.