Table 1.

Summary of key model parameters. Values refer to those used unless otherwise stated.

Label	Parameter	Value	Based on
h plaque	Biofilm thickness	250 μm	41
h saliva	Thickness of the saliva layer	250 μm	Assumed
X,Y	System box width, breadth	500 μm	Assumed
$K_A^{Gl}$	Glucose half-saturation for A	0.4 g/L	19
$K_{NA}^{Gl}$	Glucose half-saturation for NA	0.1 g/L	19
$K_A^{acid}$	Optimal [H+] for A	10−5 mol	19
$K_{NA}^{acid}$	Optimal [H+] for NA	10−7 mol	Estimated based on25
${\mu }_{max}$	Glycolysis base rate (A, NA)	5/h	42
f	Fraction of total for [polyGl]	1%	Estimated based on20
Y	Growth factor	0.1	42
Y EPS	EPS production factor	0.04	Assumed
$r_A^{death}$	Death rate for A at neutral pH	3 × 10−3/h	43
$r_{NA}^{death}$	Death rate for NA at neutral pH	6 × 10−3/h	43