Table 3.

Functional annotation of 102 cis and 45 trans-pQTL associated to proteins level at baseline

Function	Cis regulation			Trans regulation
	Count	Proportion	Corrected p value	Count	Proportion	Corrected p value
3′downstream	0	0	1	1	0.022	1
5′upstream	9	0.088	0.00061	4	0.089	0.057
5′utr	1	0.01	1	1	0.022	0.5
coding	10	0.098	0.00022	1	0.022	1
intergenic	30	0.294	1	16	0.356	1
intronic	51	0.5	1	22	0.489	1
non-coding intronic	1	0.01	0.22	0	0	1

p value from two-tailed Fisher’s exact test for enrichment analysis of pQTL SNPs among regulatory elements were adjusted for multiple testing using Bonferroni correction