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. 2017 Dec 12;7:17364. doi: 10.1038/s41598-017-17351-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of cervical lesion putative biomarkers using LEfSe. (a) Histogram of the LDA scores (log 10) showing bacteria that presented higher relative abundance in cervical lesions (red) when compared to normal cytology. Only statistically significant differences are shown. (b) Histograms showing the relative abundance of the five distinct taxa for each sample in the lesion and normal groups, separated by a thick black line. The solid and dotted black lines in the graphs indicate the mean and median relative abundance values for each group, respectively. The relative abundance (y-axis) is represented as a fraction of 1. (c) The p-values obtained by the LfESe analysis and the corrected p-values (q-values) are shown.